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The Sclerograft™ Procedure

Understanding Bone Cysts and a new Minimally Invasive Treatment Option

What is a Bone Cyst

Overview for Parents

  • A bone cyst is a pocket of fluid inside the bone.

  • Most are benign (not cancerous).

  • Bone cysts are most commonly seen in children, especially in the arm and leg bones

  • They can make bones weak and can cause a fracture

  • Some cysts can heal spontaneously once a child reaches skeletal maturity and some can heal completely after a fracture

Two Main Types:

  1. Unicameral (Simple) Bone Cysts (UBC):

    • The more common type of bone cyst which is made up of a single cyst

  2. Aneurysmal Bone Cysts (ABC):

    • Made up of multiple small cysts and can be more locally aggressive than UBCs. They are associated with higher recurrence rates than UBCs

girl in black crew neck t-shirt smiling
girl in black crew neck t-shirt smiling
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boy in black t-shirt hugging girl in red and white polka dot dress

Symptoms and Diagnosis

Common Symptoms

  • Mild, dull ache or swelling

  • Limited movement

  • A fracture that seems “too easy”

  • Found incidentally on an X-ray

Diagnosis Tools:

  • X-rays: show a hollow area in the bone with thinning of the bone wall

  • MRI: Helps characterize the bone cyst and differentiate between a UBC and an ABC

  • Biopsy: sometimes a biopsy is done to ensure that the lesion is a standard bone cyst and not something more concerning

Traditional Treatment Options

Observation:
Small, stable cysts that are not symptomatic may just be watched with X-rays — no immediate procedure needed.

If a cyst is symptomatic or getting larger and there there is concern for fracture, a procedure may be recommended.

Minimally Invasive Injections:

  • A doctor places a thin needle into the cyst to drain the fluid and may inject steroids

  • This is an outpatient procedure which is performed under general anesthesia and often requires serial injections. Adequate healing can take 6-12 months.

Open Surgery (Curettage):

  • In this surgical procedure which is done with general anesthesia, the cyst is aspirated and the wall line is scraped out of the bone.

  • The doctor may fill the hole with bone graft or cement.

  • Recovery usually takes a few months.

Sclerograft™ Procedure

Overview

The Sclerograft procedure is a minimally invasive outpatient procedure using to treat bone cysts.

Utilizing needles, chemical sclerosis destroys the cyst wall and regenerative bone graft is injected via the needles to expedite bone healing.

How It Works

  1. The procedure is done under general anesthesia

  2. The doctor uses imaging guidance (like X-ray or ultrasound) to guide needles into the cyst.

  3. Chemical sclerosis using chemicals like doxycycline are washed through the cyst to kill the cyst wall lining

  4. Regenerative bone graft is then injected through the needles and the needles are removed. The bone graft is temporary and is eventually reabsorbed by the body.

Benefits

  • No large incision. Needle incisions are closed with a bandaid

  • Quick recovery and bone formation seen between 6 weeks to 3 months

  • Low recurrence rates

  • Proven success in both UBCs and ABCs

Post-Operative Recovery

Incisions

As a minimally invasive procedure, the incisions are small enough to be closed with a bandaid and do not require stitches. The dressing can be removed in 48 hrs and usually by 3 months, most incision sites are not visible

Pain Control

If a nerve block is successfully performed prior to the procedure, most patients wake up pain free and are discharged home without any narcotics. Tylenol and advil is recommended for the first 48 hours when post-operative swelling is the greatest.

Follow-up

Bone thickening begins to occur after approximately 6 weeks, so if you child is in a sling or uses crutches, that will be continued until the first x-ray is obtained.

Follow-up imaging is usually obtained at 6 weeks, 3 months, 6 months, 12 months and annually for at least 3 years.

The decision to return to normal physical activity is driven by how well the bone has healed based on the follow-up x-rays.

The long term follow-up with x-rays is critical because of the possibility of bone cyst recurrence. Generally, if a recurrence occurs, it tends to be noticeable by the 6 month mark

The Science

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A close-up image of a doctor explaining treatment options to a patient.
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A comforting image of a child receiving care in a medical setting.

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